Which of the following constitutes a human effect that triggers priority investigation criteria?

The correct choice highlights that death, serious injury, or illness constitutes a significant human effect that triggers priority investigation criteria. This is because such outcomes are critical indicators of a potentially severe environmental or occupational hazard requiring immediate attention.

In investigation and environmental monitoring practices, prioritizing serious incidents that result in death or grave injury is essential to ensure prompt action to prevent further harm and to mitigate risks to public health. The emphasis on these severe outcomes stems from the need to protect populations from significant threats that could arise from environmental contamination, unsafe working conditions, or similar issues.

Assessing human impacts in this manner underscores the urgency of addressing potential sources of harm, thereby enabling effective interventions to safeguard the well-being of individuals and communities.